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ea0099rc5.5 | Rapid Communications 5: Pituitary and Neuroendocrinology | Part I | ECE2024

CRH-stimulated oxytocin in patients with hypopituitarism and hypothalamic damage: A randomized, single-blind, crossover, placebo-controlled trial

Asla Roca Queralt , Garrido Sanchez Maite , Urgell Rull Eulalia , Terzan Molina Silvia , Santos Vives Alicia , Fernandez Miro Merce , Varghese Nimmy , Atila Cihan , Calabrese Anna , Biagetti Betina , Christ-Crain Mirjam , Eckert Anne , Webb Susan M , Lawson Elizabeth A , Aulinas Maso Ana

Introduction: Disruption of the hypothalamic/pituitary axes may lead to hypopituitarism. Anterior pituitary deficiencies (APD) and arginine-vasopressin deficiency (AVP-D) are well established and are treated with hormone replacement. Over the last decade, preliminary studies support the presence of an oxytocin (OXT)-deficient state that might be clinically relevant in patients with hypopituitarism and hypothalamic damage (HHD). Therefore, identifying a provocative test to diag...

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CRH-stimulated oxytocin in patients with hypopituitarism and hypothalamic damage: A randomized, single-blind, crossover, placebo-controlled trial

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